You can setup an Out of Office automatic reply on your email account to let senders know you may not read their email for a certain amount of time.
To setup an Automatic Reply, first click the Options button and select See All Options... from the menu.
Next, click Organize E-Mail, then Automatic Replies.
You can choose to switch automatic replies on or off, choose the time period to send them in and set the text of the message to send. When you are finished editing your Automatic Reply click Save to ensure it is set.